CD94 Antibody [18d3] (FITC)
| Code | Size | Price |
|---|
| PSI-98-971-0.5mg | 0.5mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [18d3]
Regulatory Status: RUO
Target Species: Mouse
Application: Immunohistochemistry- Frozen Section (IHC-F)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Kp43, KLRD1
Application Note:
CD94 Antibody [18d3] for use in flow cytometry assays.
Background:
The monoclonal antibody 18d3 reacts with the mouse CD94 receptor subunit, a type II transmembrane glycoprotein. CD94 is expressed on the surface of NK cells, NK T cells, and some memory phenotype CD8+ cells. When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1b and results in a CD94high population by flow cytometry. Approximately half of NK cells do not express NKG2A, C or E; these cells express CD94 on the surface in a form that does not bind Qa-1b and is believed to be nonfunctional, producing a CD94low population by flow cytometry. CD94 is thought to play a role in the adhesion and activation of the NK cell lineage.
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CHO cells transfected with the B6 allele of CD94
NCBI Gene ID #:
16643
NCBI Official Name:
killer cell lectin-like receptor, subfamily D, member 1
NCBI Official Symbol:
Klrd1
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
O54707
Research Area:
Immunology
SPECIFICITY:
CD94
Swissprot #:
O54707
User NOte:
Optimal dilutions for each application to be determined by the researcher.