NKG2-A/C/E Antibody [20d5] (PE)
| Code | Size | Price |
|---|
| PSI-98-950-0.1mg | 0.1mg | £505.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [20d5]
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
NKG2A, NKG2C, NKG2E
Application Note:
NKG2-A/C/E Antibody [20d5] for use in flow cytometry assays.
Background:
The monoclonal antibody 20d5 reacts with an epitope common to the NKG2A, NKG2C and NKG2E isoforms of the NKG2 heterodimer, a member of the c-type lectin family of inhibitory receptors. Mouse NKG2 is a natural killer (NK) cell receptor for the non-classical MHC class I molecule Qa-1b. NKG2 is expressed on NK cells, lymphokine-activated killer (LAK) T cells, and some CD8+ memory T cells. Two-color immunofluorescent staining with the 20d5 antibody reveals two distinct NKG2+ phenotypes within the NK1.1+CD3- spleen cell population: NKG2hi (50%) and NKG2low (50%). With the exception of DBA/2J mice, NKG2 is expressed on NK1.1+ cells from all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL).
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
0.1 mg/mL
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CHO cells transfected with B6 allele of NKG2A gene
NCBI Gene ID #:
16641/16642/58179
NCBI Official Name:
killer cell lectin-like receptor subfamily C, member 1
NCBI Official Symbol:
Klrc1
NCBI Organism:
Mus musculus
Physical State:
Liquid
Research Area:
Immunology
SPECIFICITY:
NKG2-A/C/E
User NOte:
Optimal dilutions for each application to be determined by the researcher.