H-2Dd Antibody [34-5-8S] (FITC)
| Code | Size | Price |
|---|
| PSI-99-081-0.5mg | 0.5mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [34-5-8S]
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunohistochemistry- Frozen Section (IHC-F)
- Immunoprecipitation (IP)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
MHC Class I
Application Note:
H-2Dd Antibody [34-5-8S] for use in flow cytometry and immunocytochemistry assays.
Background:
The monoclonal antibody 34-5-8S reacts with a conformational epitope on H-2Dd MHC Class I found on the N-terminal domains of alpha1 and alpha2 chains when complexed with beta2-microglobulin. The antibody does not react with H-2Dd alpha chains synthesized in vitro. Weak cross-reactivity with cells from mice of the H-2b, H-2q, and H-2s haplotypes has been observed by flow cytometric analysis. Reactivity with cells from mice of the H-2f, H-2k, H-2p, and H-2r haplotypes has not been observed. 34-5-8S has been reported to block the recognition of H-2Dd by Ly-49A+, Ly-49C+, and Ly-49G2+ natural killer cells.
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
BDF1 mouse splenocytes
NCBI Gene ID #:
14964
NCBI Official Name:
histocompatibility 2, D region locus 1
NCBI Official Symbol:
H2-D1
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P01899
Research Area:
Cancer,Obesity,Signal Transduction
SPECIFICITY:
H-2Dd
Swissprot #:
P01899
User NOte:
Optimal dilutions for each application to be determined by the researcher.