Ly-49F Antibody [HBF-719]
| Code | Size | Price |
|---|
| PSI-98-942-0.5mg | 0.5mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: [HBF-719]
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Ly-49
Application Note:
Ly-49F Antibody [HBF-719] for use in flow cytometry assays.
Background:
The monoclonal antibody HBF-719 reacts with the B6 allele of Ly49F, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been downregulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The HBF-719 antibody stains ~11% of NK1.1+CD3- splenocytes, and 3.5% (2.5 month old) to 10.0% (11 month old) of CD8+ spleen cells from C57BL/6 mice.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CHO-K1 cells transfected with B6 allele of Ly49F gene
NCBI Gene ID #:
16637
NCBI Official Name:
killer cell lectin-like receptor, subfamily A, member 6
NCBI Official Symbol:
Klra6
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
Q60653
Research Area:
Immunology
SPECIFICITY:
Ly-49F
Swissprot #:
Q60653
User NOte:
Optimal dilutions for each application to be determined by the researcher.