CD11a Antibody [I21/7]
| Code | Size | Price |
|---|
| PSI-98-626-0.5mg | 0.5mg | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [I21/7]
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunocytochemistry (ICC)
- Immunohistochemistry- Frozen Section (IHC-F)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
LFA-1, LFA-1alpha, integrin alphaL
Application Note:
CD11a Antibody [I21/7] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.
Background:
The monoclonal antibody I21/7 reacts with the alpha subunit of mouse and human CD11a, also known as LFA-1, and a member of the integrin family of cell adhesion molecules. The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow. CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Costimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Whole BW5147 cells
NCBI Gene ID #:
16408
NCBI Official Name:
integrin alpha L
NCBI Official Symbol:
Itgal
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P24063
Research Area:
Cancer
SPECIFICITY:
CD11a
Swissprot #:
P24063
User NOte:
Optimal dilutions for each application to be determined by the researcher.