IGF-1 Antibody [IGF1/1020]
| Code | Size | Price |
|---|
| PSI-33-409-100ug | 100ug | £765.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: IGF1/1020
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rabbit
- Rat
Application: Immunofluorescence (IF)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Documents
Further Information
Additional Names:
IGF1, OTTHUMP00000195084, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor 1, IGFI, IGF1A, IBP1
Application Note:
Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
Immunofluorescence: 1-2 ug/ml
Functional Activity: In-vitro neutralization of biological activity of IGF-1 (Order SAF formulation)
Optimal dilution of the IGF-1 antibody should be determined by the researcher.
Immunofluorescence: 1-2 ug/ml
Functional Activity: In-vitro neutralization of biological activity of IGF-1 (Order SAF formulation)
Optimal dilution of the IGF-1 antibody should be determined by the researcher.
Background:
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Full-length recombinant human IGF1 protein was used as the immunogen for the IGF-1 antibody.
NCBI Gene ID #:
3479
NCBI Official Name:
insulin-like growth factor 1 (somatomedin C)
NCBI Official Symbol:
IGF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Immunology
Swissprot #:
P05019
User NOte:
Optimal dilutions for each application to be determined by the researcher