TGF-a Antibody [SPM357]

ProSci
Product Code: PSI-34-169
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-34-169-100ug100ug£765.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: SPM357
Regulatory Status: RUO
Target Species:
  • Bovine (Cattle)
  • Human
  • Mouse
  • Rat
Application: Immunofluorescence (IF)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

Further Information

Additional Names:
TFGAProtransforming growth factor alpha, EGF-like TGF, TGF-alpha
Application Note:
Flow Cytometry: 0.5-1 ug/million cells in 0.1ml

Immunofluorescence: 1-2 ug/ml

The optimal dilution of the TGF-a antibody for each application should be determined by the researcher.
Background:
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF-a is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A 17-amino acid peptide from the C-terminus of the rat protein was used as the immunogen for this TGF a antibody.
NCBI Gene ID #:
7039
NCBI Official Name:
transforming growth factor, alpha
NCBI Official Symbol:
TGFA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Growth Factor,Antibody Pairs, Functional Assays
Swissprot #:
P01135
User NOte:
Optimal dilutions for each application to be determined by the researcher