Transferrin Receptor Antibody [66IG10]

ProSci
Product Code: PSI-33-208
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-33-208-100ug100ug£765.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 66IG10
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

Images

1 / 2
FACS testing of K562 cells with Alexa Fluor 488 conjugated Transferrin receptor antibody (green) and isotype control (gray).
2 / 2

FACS testing of K562 cells with Alexa Fluor 488 conjugated Transferrin receptor antibody (green) and isotype control (gray).

Further Information

Additional Names:
Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, T9, p90, CD71, Transferrin receptor protein 1, serum form, sTfR, TFRC
Application Note:
Flow Cytometry: 0.5-1 ug/million cells

IF: 1-2 ug/ml

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Transferrin receptor antibody to be titered up or down for optimal performance.
Background:
This antibody recognizes a ~90-95kDa protein which is identified as cell surface Transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. The antibody is highly specific to transferrin receptor and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of transferrin receptor. Its ligand is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human protein was used as the immunogen for this Transferrin receptor antibody.
NCBI Gene ID #:
7037
NCBI Official Name:
transferrin receptor
NCBI Official Symbol:
TFRC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Cancer,Immunology,Obesity,Signal Transduction
Swissprot #:
P02786
User NOte:
Optimal dilutions for each application to be determined by the researcher