TXNIP Antibody
| Code | Size | Price |
|---|
| PSI-33-035-100ug | 100ug | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Documents
Further Information
Additional Names:
Thioredoxin-interacting protein, BMP and activin membrane-bound inhibitor homolog, non-metastatic gene A protein, NMA
Application Note:
Western blot: 1-3 ug/ml
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Background:
TXNIP (Thioredoxin-interacting protein), also called VDUP1 (Vitamin D3 upregulated protein 1) is a member of the Arrestin family of signal transduction proteins. It is a potent tumor suppressor, blocking tumor growth via blocking cell cycle progression, and reduced expression of TXNIP is found in many tumors. One way TXNIP exerts its tumor suppressive function is by suppressing NF-kB activation, possibly via regulation of the NF-kB subunit p65.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant protein fragment from the N-terminal region of human TXNIP was used as the immunogen for this antibody.
NCBI Gene ID #:
10628
NCBI Official Name:
thioredoxin interacting protein
NCBI Official Symbol:
TXNIP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein A affinity chromatography
Research Area:
Cancer
Swissprot #:
Q9H3M7
User NOte:
Optimal dilutions for each application to be determined by the researcher