Viperin Antibody
| Code | Size | Price |
|---|
| PSI-33-037-100ug | 100ug | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Documents
Further Information
Additional Names:
RSAD2, 2510004L01Rik, cig33, cig5, vig1
Application Note:
Western blot: 3-6 ug/ml
Provided assay concentrations are suggestions only, Viperin antibody titration may be required for optimal results.
Provided assay concentrations are suggestions only, Viperin antibody titration may be required for optimal results.
Background:
Viral infection induces the interferon (IFN) response which triggers the production of an array of anti-viral proteins. Viperin (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) is expressed in response to IFN-b binding to the IFN receptor, inducing the formation of the IFN-stimulated gene factor 3 complex which then binds to the Viperin promoter. It inhibits many DNA and RNA viruses through a diverse range of mechanisms and is involved in the PRR-mediated innate immune response. Viperin has been shown to be produced in response to TLR3 and TLR4 activation, but not TLR2 and TLR5. It may be involved in the TLR7 and TLR9-induced production of type I IFN by plasmacytoid dendritic cells (pDCs).
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant protein fragment from the N-terminal region of human Viperin was used as the immunogen for this antibody.
NCBI Gene ID #:
91543
NCBI Official Name:
radical S-adenosyl methionine domain containing 2
NCBI Official Symbol:
RSAD2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein A affinity chromatography purified antibody
Research Area:
Signal Transduction
Swissprot #:
Q8WXG1
User NOte:
Optimal dilutions for each application to be determined by the researcher