anti-CD4 (mouse), mAb (GK1.5) (preservative free)

Ancell
Product Code: ANC-704-820
Product Group: Primary Antibodies
Supplier: Ancell
CodeSizePrice
ANC-704-820-100ug100 ug£208.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Isotype: Rat IgG2bkappa
Antibody Clonality: Monoclonal
Antibody Clone: GK1.5
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Functional Study
  • Immunohistochemistry (IHC)
  • Immunoprecipitation (IP)
Shipping:
BI
Storage:
+4°C

Further Information

EClass:
32160000
Form (Short):
liquid
Formulation:
50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
Mouse CTL-V4 membrane prep.
Long Description:
Monoclonal antibody. Binds to an extracellular epitope of the 55kd CD4 molecule present on a murine T cell subset. Applications: ELISA, FACS, FUNC, IHC, IP. Isotype: Rat IgG2bkappa. Clone: GK1.5. 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl. CD4 binds to MHC Class II expressed by antigen presenting cells, facilitating T cell receptor signaling.
Package Type:
Plastic Vial
Product Description:
CD4 binds to MHC Class II expressed by antigen presenting cells, facilitating T cell receptor signaling.
Purity:
>95% (SDS-PAGE)
Source / Host:
Rat
Specificity:
Binds to an extracellular epitope of the 55kd CD4 molecule present on a murine T cell subset.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at +4°C.

References

Evidence implicating L3T4 in class II MHC antigen reactivity; monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines: D.B. wilde, et al.; J. Immunol. 131, 2178 (1983) | Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule: D.P. Dialynas, et al.; J. Immunol. 131, 2445 (1983) | Long-term intratracheal lipopolysaccharide exposure in mice results in chronic lung inflammation and persistent pathology: J.H. Vernooy, et al.; Am. J. Respir. Cell Mol. Biol. 26, 152 (2002) | Suppression of Alkali Burn-Induced Corneal Neovascularization by Dendritic Cell Vaccination Targeting VEGF Receptor 2: H. Mochimaru, et al.; IOVS 49, 2172 (2008)

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