O-Phosphorylethanolamine
| Code | Size | Price |
|---|
| CDX-C0021-G025 | 25 g | £84.00 |
Quantity:
| CDX-C0021-G100 | 100 g | £267.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+20°C
Documents
Further Information
Alternate Names/Synonyms:
Colaminephosphoric acid; 2-Aminoethyl dihydrogen phosphate; O-Phosphocolamine; O-Phosphoethanolamine; Monoaminoethyl Phosphate; NSC 254167; PE-104; PEA
Appearance:
White to off-white powder.
CAS:
1071-23-4
Class:
8
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS05
Handling Advice:
Protect from light and moisture.
Hazards:
H314
InChi:
InChI=1S/C2H8NO4P/c3-1-2-7-8(4,5)6/h1-3H2,(H2,4,5,6)
InChiKey:
SUHOOTKUPISOBE-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1071-23-4. Formula: C2H8NO4P. MW: 141.06. Synthetic. Phosphorylethanolamine is an ethanolamine derivative that is used in the synthesis of two different categories of phospholipids, glycerophospholipid and sphingophospholipid. It is used as an artificial AP-substrate in a TAMRA/TAMRA fluorescence-quenching assay. Newly discovered ?phosphoethanolamine cellulose? has been shown to regulate biofilm matrix architecture and function and might be important understanding bacterial biofilms and for the generation of new cellulosic materials. Synthetic phosphorylethanolamine (PHO-S) has recently demonstrated cytotoxic activity on melanoma tumor cells associated with apoptotic effects, without any effect on normal cells, as such human normal endothelial, fibroblasts and lymphocytes cells. It has shown to have in vitro and in vivo anti-leukemia effects.
MDL:
MFCD00008178
Molecular Formula:
C2H8NO4P
Molecular Weight:
141.06
Package Type:
Vial
PG:
II
Precautions:
P280, P305+P351+P338, P310
Product Description:
Phosphorylethanolamine is an ethanolamine derivative that is used in the synthesis of two different categories of phospholipids, glycerophospholipid and sphingophospholipid. It is used as an artificial AP-substrate in a TAMRA/TAMRA fluorescence-quenching assay. Newly discovered ?phosphoethanolamine cellulose? has been shown to regulate biofilm matrix architecture and function and might be important understanding bacterial biofilms and for the generation of new cellulosic materials. Synthetic phosphorylethanolamine (PHO-S) has recently demonstrated cytotoxic activity on melanoma tumor cells associated with apoptotic effects, without any effect on normal cells, as such human normal endothelial, fibroblasts and lymphocytes cells. It has shown to have in vitro and in vivo anti-leukemia effects.
Purity:
>98% (HPLC)
Signal word:
Danger
SMILES:
OP(OCCN)(O)=O
Solubility Chemicals:
Soluble in water (50mg/ml).
Source / Host:
Synthetic
Transportation:
Excepted Quantity
UN Nummer:
3261
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) A.T. Myller, et al.; Appl. Surf. Sci. 257, 1616 (2010) | (2) A.K. Ferreira, et al.; Br. J. Cancer 109, 2819 (2013) | (3) A. Shiba, et al.; Sensors 17, E1877 (2017) | (4) A.C.L. Luna, et al.; BMC Res. Notes 11, 126 (2018) | (5) W. Thongsomboon, et al.; Science 359, 334 (2018)