CoenzymeQ10
| Code | Size | Price |
|---|
| CDX-C0661-M500 | 500 mg | £121.00 |
Quantity:
| CDX-C0661-G001 | 1 g | £188.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
CoQ10; NSC 140865; Ubidecarenone; Ubiquinone-10; Ubiquinone Q10; Q-10; Vitamin Q
Appearance:
Yellow to orange powder.
CAS:
303-98-0
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+
InChiKey:
ACTIUHUUMQJHFO-UPTCCGCDSA-N
Long Description:
Chemical. CAS: 303-98-0. Formula: C59H90O4. MW: 863.34. Synthetic. Coenzyme Q10 (CoQ10) is a component of the electron transport chain of the mitochondria and participates in aerobic cellular respiration, generating energy in the form of ATP. In its reduced form, CoQ10 acts as an antioxidant, preventing the formation of reactive oxygen species and displaying neuroprotective activity. CoQ10 deficiencies have been associated with heart failure, hypertension, parkinsonism, mitochondrial encephalomyopathies and other chronic diseases. Shown to modulate the nitric oxide pathway, inhibit LDL oxidation and suppress the down regulation of NOSIII (endothelial nitric oxide synthase, eNOS) and up-regulation of NOSII (inducible nitric oxide synthase, iNOS).
MDL:
MFCD00042919
Molecular Formula:
C59H90O4
Molecular Weight:
863.34
Package Type:
Vial
Product Description:
Coenzyme Q10 (CoQ10) is a component of the electron transport chain of the mitochondria and participates in aerobic cellular respiration, generating energy in the form of ATP. In its reduced form, CoQ10 acts as an antioxidant, preventing the formation of reactive oxygen species and displaying neuroprotective activity. CoQ10 deficiencies have been associated with heart failure, hypertension, parkinsonism, mitochondrial encephalomyopathies and other chronic diseases. Shown to modulate the nitric oxide pathway, inhibit LDL oxidation and suppress the down regulation of NOSIII (endothelial nitric oxide synthase, eNOS) and up-regulation of NOSII (inducible nitric oxide synthase, iNOS).
Purity:
>98% (T)
SMILES:
O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(CC/C=C(C)/CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)C)C)=C(C)C1=O
Solubility Chemicals:
Soluble in ethanol (1mg/ml), DMF (10mg/ml) or chloroform (20mg/ml). Insoluble in water.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) F.L. Crane; J. Am. Coll. Nutr. 20, 591 (2001) | (2) C.W. Shults; Curr. Med. Chem. 10, 1917 (2003) | (3) A.J. Young, et al; CNS Spectr. 12, 62 (2007) | (4) R. Saini; J. Pharm. Bioallied Sci. 3, 466 (2011) | (5) C.M. Quinzii & M. Hirano; BioFactors 37, 361 (2011) | (6) I. Bogeski, et al.; JACS 133, 9293 (2011) | (7) K.L. Tsai, et al.; J. Nutr. Biochem. 23, 458 (2012)