Clopidogrel bisulfate
| Code | Size | Price |
|---|
| CDX-D0505-M250 | 250 mg | £164.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
Clopidogrel bisulfate; Clopidogrel Hemisulfate; SR 25990C; (S)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogensulfate
Appearance:
White to off-white powder.
CAS:
120202-66-6
Class:
6.1 (8)
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS05,GHS06,GHS09
Handling Advice:
Protect from light and moisture.
Hazards:
H300, H314, H411
InChi:
InChI=1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)
InChiKey:
FDEODCTUSIWGLK-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 120202-66-6. Formula: C16H16ClNO2S . H2SO4. MW: 321.8 . 98.1. Synthetic. (S)-(+)-Clopidogrel is a prodrug that is metabolized by cytochrome P450 isoforms to produce an active metabolite, which is a selective, irreversible high-affinity antagonist of the platelet purinergic P2Y12 receptor. Potent antithrombotic antiplatelet agent. By inhibiting the Purinoceptor P2Y12 subtype it consequently inhibits ADP-induced platelet aggregation. (S)-(+)-Clopidogrel hydrogen sulfate is the active isomer. Compound can be used as analytical reference material.
MDL:
MFCD00876395
Molecular Formula:
C16H16ClNO2S . H2SO4
Molecular Weight:
321.8 . 98.1
Package Type:
Vial
PG:
I
Precautions:
P260, P280, P303+P361+P353, P304+P340+P310, P305+P351+P338
Product Description:
(S)-(+)-Clopidogrel is a prodrug that is metabolized by cytochrome P450 isoforms to produce an active metabolite, which is a selective, irreversible high-affinity antagonist of the platelet purinergic P2Y12 receptor. Potent antithrombotic antiplatelet agent. By inhibiting the Purinoceptor P2Y12 subtype it consequently inhibits ADP-induced platelet aggregation. (S)-(+)-Clopidogrel hydrogen sulfate is the active isomer. Compound can be used as analytical reference material.
Purity:
>98% (HPLC)
Signal Word:
Danger
SMILES:
ClC1=CC=CC=C1[C@H]([NH+]2CCC(SC=C3)=C3C2)C(OC)=O.[O-]S(=O)(O)=O
Solubility Chemicals:
Soluble in DMSO (>30mg/ml), methanol or water (>30mg/ml). Insoluble in ether.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UN Nummer:
2928
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) D.C.B. Mills, et al.; Arterioscler. Thromb. 12, 430 (1992) | (2) G. Feuerstein, et al.; Exp. Opin. Invest. Drugs 4, 425 (1995) | (3) P. Savi, et al.; BBRC 283, 379 (2001) | (4) P. Savi & J.M. Herbert; Semin. Thromb. Haemostas. 31, 174 (2005) | (5) I. von Kugelgen; Pharmacol.Ther. 110, 415 (2006) | (6) N. Ferri, et al.; Drugs 73, 1681 (2013)