N,N-Bis(phosphonomethyl)glycine
| Code | Size | Price |
|---|
| CDX-N0054-G010 | 10 g | £89.00 |
Quantity:
| CDX-N0054-G050 | 50 g | £328.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+20°C
Documents
Further Information
Alternate Names/Synonyms:
N-(Carboxymethyl)iminodi(methylphosphinic acid); Glyphosine; Glycine-N,N-bis(methylenephosphonic acid); BRN 1884944; Polaris
Appearance:
Off-white to beige powder.
CAS:
2439-99-8
Class:
8
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS05
Handling Advice:
Protect from light and moisture.
Hazards:
H318
InChi:
InChI=1S/C4H11NO8P2/c6-4(7)1-5(2-14(8,9)10)3-15(11,12)13/h1-3H2,(H,6,7)(H2,8,9,10)(H2,11,12,13)
InChiKey:
OXHDYFKENBXUEM-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 2439-99-8. Formula: C4H11NO8P2. MW: 263.08. Synthetic. A glycine-phosphonic acid compound, negatively charged at neutral pH, with immunomodulatory and anti-diabetic properties. Enhances anti-B:9-23 TCR-dependent T cell activation by modulating murine class II MHC I-Ag7-mediated B:9-23 presentation on APCs. Daily administration of glyphosine is shown to delay the onset of diabetes in NOD mice. Herbicide. A plant growth regulator. Acts as a competitive inhibitor of phoshoenolpyruvate carboxylase in plants.
MDL:
MFCD00056670
Molecular Formula:
C4H11NO8P2
Molecular Weight:
263.08
Package Type:
Vial
PG:
III
Precautions:
P280, P305+P351+P338
Product Description:
A glycine-phosphonic acid compound, negatively charged at neutral pH, with immunomodulatory and anti-diabetic properties. Enhances anti-B:9-23 TCR-dependent T cell activation by modulating murine class II MHC I-Ag7-mediated B:9-23 presentation on APCs. Daily administration of glyphosine is shown to delay the onset of diabetes in NOD mice. Herbicide. A plant growth regulator. Acts as a competitive inhibitor of phoshoenolpyruvate carboxylase in plants.
Purity:
>98% (T)
Signal word:
Danger
SMILES:
O=P(O)(O)CN(CP(O)(O)=O)CC(O)=O
Solubility Chemicals:
Soluble in water (20mg/ml). Insoluble in organic solvents.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UN Nummer:
3261
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) F.E. Podesta, et al.; Plant Cell Physiol. 28, 375 (1987) | (2) M. Galanski, et al.; J. Med. Chem. 46, 4946 (2003) | (3) B.D. Stadinski, et al.; PNAS 107, 10978 (2010) | (4) A.W. Michels, et al.; J. Immunol. 187, 5921 (2011)