Mouse anti Human bcl-xl

Nordic MuBio
Product Code: EXA-A110M
Product Group: Primary Antibodies
Supplier: Nordic MuBio
CodeSizePrice
EXA-A110M100 ug£316.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: 2H12
Regulatory Status: RUO
Target Species:
  • Mouse
  • Rat
Application: Western Blot (WB)
Shipping:
Ship at ambient temperature freeze upon arrival
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Further Information

Applications Description:
Application: Western Blot at 1-5 ug/ml.
Background:
The immunogen for the anti-human bcl-xl was a synthetic peptide corresponding to amino acids 3 to 14 of the human bcl-xl sequence. Overexpression of bcl-xl to other bcl-2 members is believed to promote cell survival. The ratio of bcl-xl to other family members is believed to modulate the apoptotic process.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Apoptosis
Formulation:
Provided as solution in phosphate buffered saline with no preservative or carrier protein added.
Functional Analysis:
Western Blotting
Immunogen:
A synthetic peptide corresponding to amino acids 3 to 14 of the human bcl-xl sequence
Positive Control:
Human, mouse and rat thymocytes
Product:
Provided as solution in phosphate buffered saline.
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Protein A/G Chromatography
Source:
Mice were immunized with a synthetic peptide corresponding to amino acids 3 to 14 of the human bcl-xl sequence.
Synonyms:
bcl-xl, mouse anti human bcl xl, bclxl
UniProt:
Q07817

References

1) L.H. Boise, et. al. (1993) Cell, 74:597-608.

2) Y.T. Hsu et. al. (1997) J. Biol. Chem., 272(21): 13829-13834

3) Y. T. Hsu et. al (1997) Proc. Natl. Acad. Sci. USA, 94: 3668-3672