Mouse anti Mouse bcl-2

Contact us
Nordic MuBio
Product Code: EXA-A140M
Product Group: Primary Antibodies
Supplier: Nordic MuBio
CodeSizePrice
EXA-A140M100 ug£316.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 10C4
Regulatory Status: RUO
Target Species:
  • Mouse
  • Rat
Application: Western Blot (WB)
Shipping:
Room Temperature
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Further Information

Applications Description:
Application: Western Blots at 1-10 ug/ml
Background:
The immunogen for the anti- mouse bcl - 2 was a synthetic peptide corresponding to amino acids 61 to 76 of the mouse bcl-2 sequence. Bcl-2 expression is associated with cell survival. The ratio of bcl-2 to other bcl-2 family members is believed to modulate apoptosis.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Apoptosis
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
A synthetic peptide corresponding to amino acids 61 to 76 of the mouse bcl-2 sequence
Product:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Protein A/G Chromatography
Source:
Mice were immunized with a synthetic peptide corresponding to amino acids 61 to 76 of the mouse bcl-2 sequence
Synonyms:
mbcl2, bcl2, mouse anti mouse bcl2
UniProt:
P10415 (Human) P49950 (Rat)

References

1) D.Vaux et. al. (1988), 355: 440-442

2) D.Hockenberry et. al. (1990) Nature, 348:334-336

3) Y.T. Hsu et. al. (1997) J. Biol. Chem., 272(21): 13829-13834

4) Y. T. Hsu et. al (1997) Proc. Natl. Acad. Sci. USA, 94: 3668-3672