Rabbit anti Human Sphingosine Kinase 2 Long Form

Antibody can be used for Western blotting (1-5 ?g/ml). Optimal concentration should be evaluated by serial dilutions.

Rat sphingosine kinase 1 catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (spp)(sphingosine + ATP = sphingosine 1-phosphate + ADP), a lipid mediator with both intra- and extracellular functions. also acts on d-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as d,l-threo-dihydrosphingosine, n,n-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol. The long form of sphingosine kinase 1, an N-terminal extension, is responsible for FceRI-mediated calcium mobilization and may play a role in other ligand mediated signaling events.

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

Lot specific, see vial

Lipid Mediators

Provided as ligand affinity purified antibody in phosphate buffered saline with 0.08% sodium azide

Western Blotting

Synthetic peptide derived from the N-terminal extension of the Sphingosine Kinase 2-L protein.

Jurkat lysate used as positive control.

Affinity Purified

Products are stable for one year from purchase when stored properly

Antigen Immunoaffiinity Purification

Sphk2-L, N-terminal-extended Sphingosine Kinase 2

Q9NRA0