Sphingomyelin Synthase 1 (SMS1)

For use with SMS1 polyclonal antibodies (Cat. No. X2065P and X1701P).

Sphingomyelin Synthase is a bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) in addition to performing the inverse reaction. The direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. It directly and specifically recognizes the choline head group on the substrate. It also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. It may not function strictly as a SM synthase and is inhibited by bacterial PC-phospholipase C inhibitor D609. It is localized to Golgi apparatus; Golgi membrane; multi-pass membrane protein. It can be possibly present on the brain, heart, kidney, liver, muscle and stomach.

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

See vial for concentration

Lipid Mediators

Provided as solution in phosphate buffered saline

Western Blotting

Synthetic peptide derived from human SMS1 protein

Unconjugated

Products are stable for one year from purchase when stored properly

SMS1, Sphingomyelin synthase 1,Transmembrane protein 23, Medulla oblongata-derived protein, Protein Mob

Q86VZ5