Rabbit anti Human Programmed cell death protein 1
| Code | Size | Price |
|---|
| EXA-X2798P | 100 ug | £316.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ship at ambient temperature freeze upon arrival
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Further Information
Applications Description:
Antibody can be used for immunohistochemistry (2-4 ?g/ml) and Western blotting (1-2 ?g/ml). Optimal concentration should be evaluated by serial dilutions.
Background:
Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
Synthetic peptide derived from the human PD1 protein.
Positive Control:
Human kidney
Product Form:
Affinity Purified
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Antigen Immunoaffiinity Purification
Synonyms:
CD279, PD1
UniProt:
Q15116
References
1. Shinohara, T., et al. ?Structure and chromosomal localization of the human PD-1 gene (PDCD1)? Genomics, 23, 704-706 (1994)
2. Fife, B.T., Pauken, K.E. ?The role of the PD-1 pathway in autoimmunity and peripheral tolerance.? Ann. N.Y. Acad. Sci., 1217, 45-59 (2011)
2. Fife, B.T., Pauken, K.E. ?The role of the PD-1 pathway in autoimmunity and peripheral tolerance.? Ann. N.Y. Acad. Sci., 1217, 45-59 (2011)