Rabbit anti Human KLF14
| Code | Size | Price |
|---|
| EXA-X2796P | 100 ug | £316.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ship at ambient temperature freeze upon arrival
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Further Information
Applications Description:
Antibody can be used for immunohistochemistry (2-4 ?g/ml) and Western blotting (1-2 ?g/ml). Optimal concentration should be evaluated by serial dilutions.
Background:
KLF14 is a member of the Kr?ppel-like factor family of transcription factors. It regulates the transcription of various genes, including TGF RII (the type II receptor for TGF ). KLF14 is expressed in many tissues, lacks introns, and is subject to parent-specific expression.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
Synthetic peptide derived from the human KLF14 protein
Positive Control:
Human tonsil
Product Form:
Affinity Purified
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Antigen Immunoaffiinity Purification
Synonyms:
Krueppel-like factor 14, BTE-binding protein 5
UniProt:
Q8TD94
References
1. Truty, M.J., et al. ?Silencing of the transforming growth factor-beta (TGFbeta) receptor II by Kruppel-like factor 14 underscores the importance of a negative feedback mechanism in TGFbeta signaling.? J. Biol. Chem., 284, 6291-6300 (2009)
2. Swamynathan, S.K. ?Kr?ppel-like factors: three fingers in control.? Hum. Genomics, 4, 263-270 (2010)
3. Parker-Katiraee, L., et al. ?Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution.? PLoS Genet., 3, e65, (2007)
2. Swamynathan, S.K. ?Kr?ppel-like factors: three fingers in control.? Hum. Genomics, 4, 263-270 (2010)
3. Parker-Katiraee, L., et al. ?Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution.? PLoS Genet., 3, e65, (2007)