Rabbit anti Human NUMB
| Code | Size | Price |
|---|
| EXA-X2352P | 100 ug | £316.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ship on gel ice store at -20°C immediately upon arrival
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Further Information
Applications Description:
Antibody can be used for Western blotting (1:400 starting dilution) and immunohistochemistry (10-15 ?g/ml). Optimal concentration should be evaluated by serial dilutions.
Background:
Implicated in the control of cell fate decisions during development. Interacts with EPS15, LNX and NOTCH1. May interact with DUOXA1. Interacts with RALBP1 in a complex also containing EPN1 and TFAP2A during interphase and mitosis.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
Lot specific, see vial
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
Synthetic peptide derived from human Numb protein
Positive Control:
Protein found in brain, liver, testis and epithelium
Product Form:
Affinity Purified
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Antigen Immunoaffiinity Purification
Synonyms:
Protein S171; Protein numb homolog
UniProt:
P49757 (Human)
References
1. Susini, L., et al. 'Siah-1 binds and regulates the function of Numb.; Proc. Natl. Acad. Sci. U.S.A. 98:15067-15072(2001).
2. Verdi, J.M., et al. 'Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage.; Proc. Natl. Acad. Sci. U.S.A. 96:10472-10476(1999).
2. Verdi, J.M., et al. 'Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage.; Proc. Natl. Acad. Sci. U.S.A. 96:10472-10476(1999).