Rabbit anti Human Monocarboxylate Transporter 3 (MCT3)
| Code | Size | Price |
|---|
| EXA-X2361P | 100 ug | £316.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ship on gel ice store at -20°C immediately upon arrival
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Further Information
Applications Description:
Antibody can be used for Western blotting (1:400 starting dilution). Optimal concentration should be evaluated by serial dilutions.
Background:
Monocarboxylate Transporter 3 (MCT3) is a proton-linked monocarboxylate transporter. It catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
Lot specific, see vial
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
Synthetic peptide derived from MCT3 protein.
Positive Control:
Retinal pigment epithelium
Product:
Provided as a solution in Tris buffered saline with 0.08% sodium azide, 10mM MgCl2, 10mM ammonium sulfate, and 0.2% lactose.
Product Form:
Affinity Purified
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Antigen Immunoaffiinity Purification
Synonyms:
Solute carrier family 16 member 8; MCT3; SLC16A8
UniProt:
O95907 (Human)
References
1. Yoon, H., et al. Cloning of the human monocarboxylate transporter MCT3 gene: localization to chromosome 22q12.3-q13.2.; Genomics 60:366-370(1999).
2. Zhu, S., et al. 'Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis.' Circulation. 2005 Aug 30;112(9):1353-61.
3. Philip, N.J., et al. 'Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse.' Invest Ophthalmol Vis Sci. 2003 Mar;44(3):1305-11.
2. Zhu, S., et al. 'Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis.' Circulation. 2005 Aug 30;112(9):1353-61.
3. Philip, N.J., et al. 'Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse.' Invest Ophthalmol Vis Sci. 2003 Mar;44(3):1305-11.