Sheep anti Avian TGF beta II receptor (77-148)
| Code | Size | Price |
|---|
| EXA-L115P | 100 ug | £316.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Sheep
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Avian
Shipping:
Room Temperature
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Further Information
Applications Description:
Western Blot (1:100), Immunohistochemistry
Background:
Epithelial-mesenchymal transformation is a critical event in the development of many organ systems including heart. Transforming Growth Factor (TGF ) is one of a number of factors that mediates this transformation.Antibodies directed against TGF Type II recepttor block both the endicardial cell activation and subsequent migration that constitute transformation in the chick atrioventricular (AV) cushion.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Signal Transduction
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Immunohistochemistry
Immunogen:
Protein containing chick transforming growth factor type II receptor a.a.77-148.
Positive Control:
Recombinant proteins conjugated to OVA, GST, His tags and other. Native TGF beta II proteins.
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Ammonium Sulfate Precipitation
Synonyms:
TGBb Type II r; TGF beta II receptor; transforming growth factor receptor beta, Type II
UniProt:
Q90999 (Chicken)
References
1) C. Brown, et. al. (1999) Dev. Dynamics, 1-7