Rabbit anti Human ADAM DEC1

Antibody can be used for Western blotting (1:400 dilution) and immunohistochemistry on paraffin embedded tissues (2-10 ?g/ml). Optimal concentration should be evaluated by serial dilutions.

ADAMDEC1 is expressed in the immune system, by dendritic cells and macrophages. It may play an important role in the control of the immune response and during pregnancy.1 Due to the partial lack of a disintegrin domain and the total lack of a cysteine-rich domain, this protein has been placed in a novel subclass of the ADAM gene family2.

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

See vial for concentration

Signal Transduction

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Western Blotting

Synthetic peptide derived from the human ADAMDEC1 protein.

Expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. Predominantly expressed in dendritic cells (DC) of the germinal center. Weakly expressed in monocyte and highly expressed in macrophage. Absent in immature DC.

Affinity Purified

Reagents are stable for the period shown on the vial label when stored properly

Antigen Immunoaffiinity Purification

A disintegrin and metalloproteinase domain-like protein decysin 1,ADAM-like protein decysin 1

O15204