Rabbit anti Human Stanniocalcin-1 (STC1)

Nordic MuBio
Product Code: EXA-X2666P
Product Group: Primary Antibodies
Supplier: Nordic MuBio
CodeSizePrice
EXA-X2666P100 ug£316.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
Ship at ambient temperature freeze upon arrival
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Further Information

Applications Description:
Antibody can be used for immunohistochemistry (10-15 ?g/ml). Optimal concentration should be evaluated by serial dilutions.
Background:
Stanniocalcin 1 is a secreted disulfide-linked homodimeric glycoprotein belonging to the stanniocalcin family of proteins. It is widely expressed and has endocrine/paracrine/autocrine functions relating to calcium and phosphate homeostasis, reproduction, and development. In the ovary, it has been shown to be a paracrine hormone that regulates granulosa cell function. It also has been known to. stimulate renal phosphate reabsorption, and could therefore prevent hypercalcemia.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Signal Transduction
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
Synthetic peptide derived from the human STC-1 protein.
Positive Control:
Expressed in most tissues, with the highest levels in ovary, prostate, heart, kidney and thyroid. In the kidney, expression is confined to the nephron, specifically in the distal convoluted tubule and in the collecting tubule. Not detected in the brain, liver, spleen, peripheral blood leukocytes,adrenal medulla.
Product Form:
Affinity Purified
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Antigen Immunoaffiinity Purification
Synonyms:
STC1
UniProt:
P52823

References

1. Jeffrey K.J., Reddel R.R., 'Characterization of the human stanniocalcin 1 gene.
Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases

2. Olsen H.S., Cepeda M.A., Zhang Q.-Q., Rosen C.A., Vozzolo B.L., Wagner G.F., Human stanniocalcin: a possible hormonal regulator of mineral metabolism.
Proc. Natl. Acad. Sci. U.S.A. 93:1792-1796(1996) [PubMed: 8700837] [Abstract]