Rabbit anti Human DDX4
| Code | Size | Price |
|---|
| EXA-X2750P | 100 ug | £316.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ship at ambient temperature freeze upon arrival
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Further Information
Applications Description:
Antibody can be used for immunohistochemistry (2-5 ?g/ml at pH 6.2) and Western blot (1-5 ?g/ml). Optimal concentration should be evaluated by serial dilutions.
Background:
DDX4 is an ATP-dependent DEAD-box RNA helicase found in the chromatoid body of the germ cells (1). This enzyme is specific to germ cells and is necessary for germ cell development (2). Mouse DDX4 was shown to interact with Dicer, suggesting a role in microRNA-mediated RNA silencing (1).
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Signal Transduction
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
Synthetic peptide derived from the human DDX4 protein
Positive Control:
Human testis tissue
Product Form:
Affinity Purified
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Antigen Immunoaffiinity Purification
Synonyms:
Probable ATP-dependent RNA Helicase DDX4; MVH; DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
UniProt:
Q9NQI0
References
1. Kotaja, N., et al. ?The chromatoid body of male germ cells: similarity with processing bodies and presence of Dicer and microRNA pathway components.? Proc. Natl. Acad. Sci., 103, 2647-2652 (2006)
2. Albamonte, M.S., et al. ?The developing human ovary: immunohistochemical analysis of germ-cell-specific VASA protein, BCL-2/BAX expression balance and apoptosis.? Hum. Reprod. 23, 1895-1901 (2008)
2. Albamonte, M.S., et al. ?The developing human ovary: immunohistochemical analysis of germ-cell-specific VASA protein, BCL-2/BAX expression balance and apoptosis.? Hum. Reprod. 23, 1895-1901 (2008)