Nordic MuBio

Sodium/hydrogen exchanger 1

Product Code:
 
EXA-X2339B
Product Group:
 
Peptides
Supplier:
 
Nordic MuBio
Host Type:
 
Rabbit
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Ship at ambient temperature freeze upon arrival
Storage:
 
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
 

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EXA-X2339B50 ug£162.00
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  • Further Information
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Further Information

Applications Description:
For use with NHE1 polyclonal antibodies (Cat. No. X2315P & X2338P).
Background:
NHE-1 is involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. NHE-1 plays an important role in signal transduction. Located in the kidney and intestine.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Signal Transduction
Formulation:
Provided as solution in phosphate buffered saline
Functional Analysis:
Western Blotting
Immunogen:
Synthetic peptide derived from the human NHE-1 protein
Positive Control:
Protein expressed in kidney and intestine.
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Synonyms:
Sodium/hydrogen exchanger 1; NHE-1; SL9A1; Solute carrier family 9 member 1
UniProt:
P19634

References

1. Pang, T., et al. 'Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchanger.; J. Biol. Chem. 277:43771-43777(2002).

2. Slepkov, E.R., et al. 'Proline residues in transmembrane segment IV are critical for activity, expression and targeting of the Na+/H+ exchanger isoform 1.; Biochem. J. 379:31-38(2004).

3. Slepkov, E.R., et al. 'Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger.; J. Biol. Chem. 280:17863-17872(2005).