Mouse anti Human p19 - ink4d
| Code | Size | Price |
|---|
| EXA-C165M | 100 ug | £316.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: DCS100
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blot (WB)
Shipping:
Room Temperature
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Further Information
Applications Description:
Applications: Western Blot, Immunoistochemistry, Immunoprecipitation (co-precipitates cdk4/cdk6)
Background:
The immunogen for the anti-h-p19 was a his-tagged recombinant full length p19 protein recognizing a 19kD protein. The p19ink4d tumor suppressor protein shows no cross reactivity with the closely related inhibitors including p16 ink4a and p15ink4b. p19nk4d is a specific inhibitor of cdk4/cdk6 and is periodically expressed during cell cycle. It is maximally induced as cells enter S phase.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Cell Cycle
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
A his-tagged recombinant full length p19 protein recognizing a 19kD protein
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Protein A/G Chromatography
Synonyms:
hp19; p19 ink4d; CDKN2D; Cyclin-dependent kinase 4 inhibitor D
UniProt:
P55273 (Human)
References
1)H. Hirai, et. al. (1995) Mol. Cell. Biol. (15) 2672-2681