Mouse anti Human p21 WAF-1
| Code | Size | Price |
|---|
| EXA-C160M | 100 ug | £316.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: DCS-60
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blot (WB)
Shipping:
Room Temperature
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Further Information
Applications Description:
Applications: 1-5 ug /ml for Western Blot, Immunoflurescence, Immunoprecipitation (co-precipitates cdk4/cdk6)
Background:
The immunogen for the anti-hp21 was a recombinant full length p21protein recognizing a 21kDa protein. The p21waf1 tumor suppressor protein shows no cross reactivity with the closely related inhibitors .p21waf1 is a specific inhibitor of cdk?s, and is a tumor suppressor involved in the pathogenesis of a number of malignancies including colon and breast carcinoma
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Cell Cycle
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
A recombinant full length p21protein recognizing a 21kDa protein
Product:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Protein A/G Chromatography
Source:
Mice were immunized with a recombinant full length p21 protein.
Synonyms:
p21waf1; hp21; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6
UniProt:
P38936 (Human)
References
1) R. Erber, et.al. (1997) Pred. Oncol. 74, 383-389
2. Shen, J., et al. ?Identification and Validation of Differences in Protein Levels in Normal, Premalignant, and Malignant Lung Cells and Tissues Using High-Throughput Western Array and Immunohistochemistry.? Cancer Res., 66, 11194-11206 (2006).
2. Shen, J., et al. ?Identification and Validation of Differences in Protein Levels in Normal, Premalignant, and Malignant Lung Cells and Tissues Using High-Throughput Western Array and Immunohistochemistry.? Cancer Res., 66, 11194-11206 (2006).