Mouse anti Human Fetoprotein
| Code | Size | Price |
|---|
| EXA-X1841M | 100 ug | £316.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: C3
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
- Porcine (pig)
Application: Immunohistochemistry (IHC)
Shipping:
Ship at ambient temperature freeze upon arrival
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Further Information
Applications Description:
Antibody can be used for immunohistochemistry on formalin-fixed, paraffin embedded tissues (1-5 ?g/ml). Optimal concentration should be evaluated by serial dilutions.
Background:
Alpha-Feto Protein (AFP) is a protein produced by the fetus, which is excreted into the amniotic fluid and into the mother's bloodstream through the placenta. The amount of AFP, both in the maternal?s blood and in the amniotic fluid, at particular periods during the pregnancy, may be associated with the presence of neural tube defects or chromosomal problems in the baby. AFP synthesis occurs in tissues including the gut, liver and fetal yolk sac. AFP expression may be seen in germ cell neoplasma and in liver carcinoma.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Signal Transduction
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Immunohistochemistry
Immunogen:
Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with purified human alpha-fetoprotein and mouse myeloma cells.
Positive Control:
HepG2 cells
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Protein A/G Chromatography
Synonyms:
AFP
References
1. Yazova AK; et al. 'Human alpha-fetoprotein epitopes as revealed by monoclonal antibodies.' Immunology Letters, 1990 Sep, 25(4):325-30.
2. Sato, Y., et al. 'Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.' Blood, 106, 756-763 (2005).
2. Sato, Y., et al. 'Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.' Blood, 106, 756-763 (2005).