Rabbit anti Human Sphingomyelin Synthase 1 (Peptide as antigen)

Antibody can be used for Western blotting (5-10 ?g/ml). Optimal concentration should be evaluated by serial dilutions.

A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus; Golgi membrane; multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

See vial for concentration

Signal Transduction

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Western Blotting

Synthetic peptide derived from the mouse sphingomyelin synthase 1 protein

Brain, heart, kidney, liver, muscle and stomach.

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Unconjugated

Products are stable for one year from purchase when stored properly

Ammonium Sulfate Precipitation

Rabbits were immunized with a synthetic peptide derived from the mouse sphingomyelin synthase 1 protein

Phosphatidylcholine:ceramide cholinephosphotransferase 1 Transmembrane protein 23, Sphingomyelin synthase 1, Mob protein

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