Mouse anti Human myc

Application: Western Blot, Immunoprecipitation (both with and without SDS), Immunofluorescence, Frozen Sections -- Myc is a labile protein, therefore preotease inhibitors should be used at all times.

Human c-myc belongs to a family of 5 myc oncogenes. Amplification of c-myc has been found in several types of human tumors including breast and colon carcinomas. Induction of c-myc in cells grown in the appropriate growth factors or co-expression with survival genes, such as bcl-2 causes cell proliferation. In the abscence of these factors, c-myc expression causes cell death. c-myc gene gives rise to at least two nuclear phosphoproteins of 64kDa and 67kDa, the unphosphorylated form is 49kDa.

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

See vial for concentration

Signal Transduction

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Western Blotting

Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant full-length human c-Myc protein and mouse myeloma cells.

Unconjugated

Antibodies are stable for one year from purchase if stored frozen

Protein A/G Chromatography

Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant full-length human c-Myc protein and mouse myeloma cells.

cmyc; Myc proto-oncogene protein; transcription factor p64

P01106 (Human)P01108 (Mouse)P09416 (Rat)