Mouse anti Human p130

Western Blots at 1:1000

The immunogen used was a recombinant protein to the N terminus of p130. p130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107(collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors. This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130kDa.

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

See vial for concentration

Cell Cycle

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Western Blotting

Recombinant protein to the N terminus of p130

This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130kDa. And is suitable for use in western blot with his- tagged or GST tagged proteins.

Monoclonal antibody provided as solution in phosphate buffered saline with 0.08% sodium azide

Unconjugated

Products are stable for one year from purchase when stored properly

Protein A/G Chromatography

The immunogen used was a recombinant protein to the N terminus of p130.

p130; Retinoblastoma-like protein 2; RBR-2; PRB2

Q08999 (Human)Q64700 (Mouse)O55081 (Rat)