Mouse anti Human p107

Applications: Western Blots at 1:1000

The immunogen used was a recombinant protein to the N terminus of p107. p107 is related both in structure and function to the retinoblastoma tumor suppressor protein and p130 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p107 converts E2F transcription factors from transcriptional activators to transcriptional repressors. KAB6 recognizes both the phosphorylated and unphosphorylated forms of p107 at a MW of 107kDa.

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

See vial for concentration

Cell Cycle

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Western Blot

Recombinant GST protein to the N terminus of p107

KAB6 recognizes both the phosphorylated and unphosphorylated forms of p107 at a MW of 107kDa.

Unconjugated

Antibodies are stable for one year from purchase if stored frozen

Protein A/G Chromatography

The immunogen used to immunize the mice was a recombinant GST protein coupled to the N-terminus of p107.

p107; Retinoblastoma-like protein 1; PRB1; 107 kda retinoblastoma-associated protein

P28749 (Human)Q64701 (Mouse)