Rabbit anti Human Protein Phosphatase 2 A/B gamma
Code | Size | Price |
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EXA-P180P | 100 ug | £316.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Bovine (Cattle)
- Human
- Mouse
- Rat
Shipping:
Ship at ambient temperature freeze upon arrival
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Further Information
Applications Description:
Detects PP2A/B isoforms by Western blot analysis. Detects a 56 kDa band in whole rat brain homogenates. Optimal concentration should be evaluated by serial dilutions.
Background:
Protein phosphatase 2A (PP2A) is a hetertrimeric enzyme consisting of a catalytic subunits (C), a structural subunit (A) and a variable regulatory subunit (B). The B subunit family is made up of the , and isoforms. The PP2A/B isoform appears to only be detectable in the brain where it has been speculated that it cytoskeletal substrates. The RNA which produces the PP2A/B is developmentally regulated and increases sharply after birth. It has also been suggested that it may be important in the establishment and maintenance of neuronal connections.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Signal Transduction
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
Antibody raised against synthetic peptide corresponding to amino acids 53 to 66 of the mammalian protein phosphatase 2 A/B conjugated to KLH.
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Ammonium Sulfate Precipitation
Synonyms:
Protein Phosphatase 2 A/B?2
UniProt:
Q13362 (Human)P97888 (Rat)Q8BG02 (Mouse)
References
1. Strack, S., et al. Brain protein phosphatase 2A: Developmental regulation and distinct cellular and subcellular localization by B subunits. J. Comp. Neurol. 1998, 392, 515-527