Rabbit anti Rat Kv1.4 Potassium Channel

Nordic MuBio
Product Code: EXA-X1037
Product Group: Primary Antibodies
Supplier: Nordic MuBio
CodeSizePrice
EXA-X1037100 ug£316.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Rat
Shipping:
Room Temperature
Storage:
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Further Information

Applications Description:
Applications: 1- 10 ug/ml for western blot analysis, immunofluorescence, immunoprecipitation.
Background:
In neurons voltage-dependent potassium channels are key determinants of the resting membrane potential and of membrane excitability, conditioning the frequency, and shape of action potential (1). Potassium channels are encoded by numerous genes whose products can be classified into distinct subfamilies. The most distinctively characterized is that of the Kv1 shaker class (2). The rabbit anti kv 1.4 ptassium channel antibody recognizes a 90 kDa protein by western blot on rat hippocampal membranes and a protein of 76 kDa in lysates of HEK293 cells (3).
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Signal Transduction
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Product:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Product Form:
Unconjugated
Product Stability:
Antibodies are stable for one year from purchase if stored frozen
Purification Method:
Ammonium Sulfate Precipitation
Source:
Rabbits were immunized with a peptide derived from rat Kv1.4 potassium channel protein, conjugated to KLH
Synonyms:
Rabbit anti Kv1.4 Potassium Channel
UniProt:
P15385

References

  • Miller C. Science 1991: 252;1092-1096
  • Chandy K.G. et al. Handbook of receptors and channels. CRC Press 1995; 1-71.
  • Jugloff J.G.M. et al. J. Biol. Chem. 2000: 275; 1357-1364.