NHERF1 Antibody / SLC9A3R1
| Code | Size | Price |
|---|
| NSJ-RQ4707-100ul | 100ul | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: IIH-19
Regulatory Status: RUO
Target Species:
- Human
- Rat
Application: Western Blot (WB)
Storage:
Store the NHERF1 antibody at -20°C.
Documents
Further Information
Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the NHERF1 antibody should be determined by the researcher.
Description:
The SLC9A3R1 gene encodes a sodium/hydrogen exchanger regulatory cofactor. Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (also called SLC9A3 regulator 1 and Ezrin-radixin-moesin-binding phosphoprotein 50) interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human NHERF1 was used as the immunogen for the NHERF1 antibody.
Limitation:
This NHERF1 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human, Rat
Uniprot #:
O14745