CHK1 Antibody (pS296)
| Code | Size | Price |
|---|
| NSJ-RQ4710-100ul | 100ul | £535.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: FEO-3
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the phospho-Chk1 antibody (pS296) at -20°C.
Documents
Further Information
Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the phospho-Chk1 antibody (pS296) should be determined by the researcher.
Description:
The protein encoded by CHEK1 belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide human Chk1 / CHEK1 (surrounding pS296) was used as the immunogen for the phospho-Chk1 antibody (pS296).
Limitation:
This phospho-Chk1 antibody (pS296) is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
O14757