Exportin 1 Antibody / XPO1 / CRM1

NSJ Bioreagents
Product Code: NSJ-RQ4719
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ4719-100ul100ul£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: AEFD-24
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store the CRM1 antibody at -20°C.

Images

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Western blot testing of human HeLa cell lysate with CRM1 antibody. Predicted molecular weight ~123 kDa.

Western blot testing of human HeLa cell lysate with CRM1 antibody. Predicted molecular weight ~123 kDa.

Further Information

Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the CRM1 antibody should be determined by the researcher.
Description:
Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human CRM1 / XPO1 was used as the immunogen for the CRM1 antibody.
Limitation:
This CRM1 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
O14980