p73 Antibody / Tumor Protein 73

Western blot: 1:500-1:2000

Optimal dilution of the p73 antibody should be determined by the researcher.

The TP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [RefSeq]

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide specific to human p73 / TP73 was used as the immunogen for the p73 antibody.

This p73 antibody is available for research use only.

Affinity purified

Human

O15350