TLR2 Antibody

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NSJ Bioreagents
Product Code: NSJ-RQ4761
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ4761-100ul100ul£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: ADH-20
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store the TLR2 antibody at -20°C.

Images

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IHC staining of FFPE human kidney tissue with TLR2 antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
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Western blot testing of human 1) A549 and 2) HeLa lysate with TLR2 antibody. Predicted molecular weight: 85-90 kDa.
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IHC staining of FFPE human kidney tissue with TLR2 antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
Western blot testing of human 1) A549 and 2) HeLa lysate with TLR2 antibody. Predicted molecular weight: 85-90 kDa.

Documents

Further Information

Application Details :
Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE): 1:100-1:500
Application Note:
Optimal dilution of the TLR2 antibody should be determined by the researcher.
Description:
Toll-like Receptor 2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human TLR2 was used as the immunogen for the TLR2 antibody.
Limitation:
This TLR2 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
O60603