NBS1 Antibody / NBN (pS343)

NSJ Bioreagents
Product Code: NSJ-RQ4768
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ4768-100ul100ul£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: BGI-14
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the phospho-NBS1 antibody at -20°C.

Images

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Western blot testing of etoposide-treated human Jurkat cell lysate with phospho-NBS1 antibody. Predicted molecular weight ~95 kDa.

Western blot testing of etoposide-treated human Jurkat cell lysate with phospho-NBS1 antibody. Predicted molecular weight ~95 kDa.

Further Information

Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the phospho-NBS1 antibody should be determined by the researcher.
Description:
Nijmegen breakage syndrome protein 1 (NBS1) is a component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. [UniProt]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human NBS1 / NBN (surrounding pS343) was used as the immunogen for the phospho-NBS1 antibody.
Limitation:
This phospho-NBS1 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
O60934