c-Maf Antibody / MAF

Immunohistochemistry (FFPE): 1:50-1:200

Optimal dilution of the MAF antibody should be determined by the researcher.

The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [RefSeq]

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide specific to human c-Maf / MAF was used as the immunogen for the MAF antibody.

This MAF antibody is available for research use only.

Nuclear

Affinity purified

Human

O75444