Bcl10 Antibody
| Code | Size | Price |
|---|
| NSJ-RQ4824-100ul | 100ul | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: GDB-2
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the Bcl10 antibody at -20°C.
Documents
Further Information
Application Details :
Western blot: 1:1000-1:2000
Application Note:
Optimal dilution of the Bcl10 antibody should be determined by the researcher.
Description:
Bcl10 contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. It is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. Bcl10 is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human Bcl10 was used as the immunogen for the Bcl10 antibody.
Limitation:
This Bcl10 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
O95999