Alpha-2-macroglobulin Antibody / A2M
| Code | Size | Price |
|---|
| NSJ-RQ4853-100ul | 100ul | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: ABAO-1
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the Alpha-2-macroglobulin antibody at -20°C.
Documents
Further Information
Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the Alpha-2-macroglobulin antibody should be determined by the researcher.
Description:
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human A2M / Alpha 2 Macroglobulin was used as the immunogen for the Alpha-2-macroglobulin antibody.
Limitation:
This Alpha-2-macroglobulin antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P01023