Phospho-c-Myc Antibody (pT58)
| Code | Size | Price |
|---|
| NSJ-RQ4863-100ul | 100ul | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: FOC-13
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the phospho-c-Myc antibody at -20°C.
Documents
Further Information
Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the phospho-c-Myc antibody should be determined by the researcher.
Description:
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human c-Myc (surrounding pT58) was used as the immunogen for the phospho-c-Myc antibody.
Limitation:
This phospho-c-Myc antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P01106