NRAS Antibody

NSJ Bioreagents
Product Code: NSJ-RQ4866
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ4866-100ul100ul£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: AOFE-14
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the NRAS antibody at -20°C.

Images

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Western blot testing of human SH-SY5Y cell lysate with NRAS antibody. Predicted molecular weight ~21 kDa.

Western blot testing of human SH-SY5Y cell lysate with NRAS antibody. Predicted molecular weight ~21 kDa.

Further Information

Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the NRAS antibody should be determined by the researcher.
Description:
NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. It has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in the gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human NRAS was used as the immunogen for the NRAS antibody.
Limitation:
This NRAS antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P01111