Leucyl tRNA synthetase Antibody / LARS

NSJ Bioreagents
Product Code: NSJ-RQ4955
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ4955-100ug100ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Antibody Clone: n/a
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
After reconstitution, the Leucyl tRNA synthetase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

1 / 1
Western blot testing of human 1) HL-60, 2) K562, 3) ThP-1, 4) Caco-2, 5) rat liver, 6) mouse brain, 7) mouse liver and 8) mouse NIH3T3 lysate with Leucyl tRNA synthetase antibody at 0.5ug/ml. Predicted molecular weight ~134 kDa.

Western blot testing of human 1) HL-60, 2) K562, 3) ThP-1, 4) Caco-2, 5) rat liver, 6) mouse brain, 7) mouse liver and 8) mouse NIH3T3 lysate with Leucyl tRNA synthetase antibody at 0.5ug/ml. Predicted molecular weight ~134 kDa.

Further Information

Application Details :
Western blot: 0.5-1ug/ml, Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the Leucyl tRNA synthetase antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Description:
Leucyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the LARS gene. This gene is mapped to 5q32. It encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids Q628-Q855 from the human protein were used as the immunogen for the Leucyl tRNA synthetase antibody.
Limitation:
This Leucyl tRNA synthetase antibody is available for research use only.
Purity:
Antigen affinity purified
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q9P2J5