Estrogen Receptor alpha Antibody (pS118)

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NSJ Bioreagents
Product Code: NSJ-RQ5023
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
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NSJ-RQ5023-100ul100ul£535.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: EIG-5
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the phospho-ER alpha antibody at -20°C.

Images

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Western blot testing of human MCF7 cells 1) untreated and 2) treated with b-Estradiol and EGF, with phospho-ER alpha antibody. Predicted molecular weight ~66 kDa.
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Western blot testing of human MCF7 cells 1) untreated and 2) treated with b-Estradiol and EGF, with phospho-ER alpha antibody. Predicted molecular weight ~66 kDa.

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Further Information

Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the phospho-ER alpha antibody should be determined by the researcher.
Description:
Estrogen receptor alpha is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human ER alpha / ESR1 (surrounding pS118) was used as the immunogen for the phospho-ER alpha antibody.
Limitation:
This phospho-ER alpha antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P03372